Plasma cell leukemia with soft tissue involvement; reporting a rare case
Ahmed Bendari1, Rahaf M Abu Khalaf2, Sunder Sham1
1Department of Pathology and Laboratory Medicine, Lenox Hill Hospital, Northwell Health, NY, USA.
Leukemia Research Reports
|January 29, 2024
Summary
Plasma cell leukemia (PCL), a rare aggressive cancer, can manifest as soft tissue involvement, a very uncommon presentation. This case highlights a patient with PCL exhibiting extensive extramedullary disease, including subcutaneous nodules.
Area of Science:
- Hematology
- Oncology
- Pathology
Background:
- Plasma cell leukemia (PCL) is an aggressive hematologic malignancy, a rare variant of multiple myeloma.
- Extramedullary involvement is common in PCL, but soft tissue infiltration is exceptionally rare.


