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Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
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Plasma cell leukemia with soft tissue involvement; reporting a rare case.

Ahmed Bendari1, Rahaf M Abu Khalaf2, Sunder Sham1

  • 1Department of Pathology and Laboratory Medicine, Lenox Hill Hospital, Northwell Health, NY, USA.

Leukemia Research Reports
|January 29, 2024
PubMed
Summary

Plasma cell leukemia (PCL), a rare aggressive cancer, can manifest as soft tissue involvement, a very uncommon presentation. This case highlights a patient with PCL exhibiting extensive extramedullary disease, including subcutaneous nodules.

Area of Science:

  • Hematology
  • Oncology
  • Pathology

Background:

  • Plasma cell leukemia (PCL) is an aggressive hematologic malignancy, a rare variant of multiple myeloma.
  • Extramedullary involvement is common in PCL, but soft tissue infiltration is exceptionally rare.
Keywords:
Atypical plasmacytoid cellsCD 138Plasma cell neoplasm

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