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Clinical Applications of Epidermal Stem Cells01:19

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Enzymes02:34

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Introduction to Enzymes01:22

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The use of enzymes by humans dates to 7000 BCE. Humans first used enzymes to ferment sugars and produce alcohol without knowing that this was an enzyme-catalyzed reaction. Wilhelm Kuhne coined the term 'enzyme' in 1877 from the Greek words ‘en’ meaning ‘in’ or ‘within’ and ‘zyme’ meaning ‘yeast.’
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Updated: Jul 4, 2025

Preparation of Keratin Hydrolysate from Chicken Feathers and Its Application in Cosmetics
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Enzymes for dermatological use.

Natália Santos Nascimento1, Karin Mariana Torres-Obreque1, Camila Areias Oliveira2

  • 1Department of Biochemical and Pharmaceutical Technology, School of Pharmaceutical Sciences, University of São Paulo (USP), São Paulo, Brazil.

Experimental Dermatology
|January 29, 2024
PubMed
Summary
This summary is machine-generated.

Enzymes offer specific, targeted treatments for skin health and anti-aging, addressing damage from UV radiation and environmental factors. This review explores their dermatological potential and challenges.

Keywords:
DNA repair enzymesantioxidant enzymesenzymes for topical useproteases

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Area of Science:

  • Dermatology and biochemistry, focusing on skin health and therapeutic applications.

Background:

  • The skin acts as a vital barrier against environmental stressors like UV radiation (UVR).
  • Skin aging and damage from external factors necessitate advanced therapeutic and cosmetic solutions.
  • Biomolecules, particularly enzymes, show promise due to their high specificity compared to traditional treatments.

Purpose of the Study:

  • To review the dermatological applications of enzymes for improving skin health and combating aging.
  • To explore the potential of topical enzymes in treating conditions caused by UVR and pollution.
  • To discuss the challenges and future directions in the field of dermatological enzymes.

Main Methods:

  • Literature review of studies on enzyme applications in dermatology.
  • Analysis of enzyme classes (antioxidant, proteases, repairing) for skin benefits.
  • Examination of challenges in topical enzyme delivery and efficacy.

Main Results:

  • Enzymes demonstrate potential as targeted agents for skin repair and anti-aging.
  • Specific enzyme types show promise in mitigating damage from UVR and environmental pollutants.
  • The field is growing, with ongoing research into various enzyme functionalities.

Conclusions:

  • Enzymes represent a promising class of biomolecules for advanced dermatological treatments.
  • Further research is needed to overcome challenges and optimize the use of enzymes in skincare.
  • Enzyme-based therapies offer a specific and potentially effective approach to skin health and rejuvenation.