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Updated: Jul 4, 2025

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Marine natural products.

Anthony R Carroll1,2, Brent R Copp3, Tanja Grkovic4

  • 1School of Environment and Science, Griffith University, Gold Coast, Australia. A.Carroll@griffith.edu.au.

Natural Product Reports
|January 29, 2024
PubMed
Summary
This summary is machine-generated.

This review details marine natural products (MNPs) discovered in 2022, highlighting 1417 new compounds from diverse marine organisms and their biological activities.

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Area of Science:

  • Marine Biology
  • Natural Product Chemistry
  • Pharmacognosy

Background:

  • Marine natural products (MNPs) represent a rich source of novel chemical entities.
  • The continuous exploration of marine biodiversity yields a vast array of compounds with potential applications.
  • The year 2022 saw significant advancements in the discovery and characterization of MNPs.

Purpose of the Study:

  • To comprehensively review the literature on marine natural products published in 2022.
  • To catalog newly discovered MNPs, their biological activities, and source organisms.
  • To analyze the diversity of MNP structures in relation to their biological and environmental origins.

Main Methods:

  • Systematic literature search for publications from January to December 2022.
  • Identification and extraction of data on new MNPs, biological activities, source organisms, and geographical origin.
  • Analysis of MNP structure classes and their correlation with biota and biome.

Main Results:

  • A total of 645 citations were reviewed, focusing on 1417 new marine natural products reported in 384 papers.
  • Compounds were isolated from a wide range of marine sources including microorganisms, algae, sponges, and invertebrates.
  • Included are details on biological activities, biosynthetic studies, and synthetic efforts for selected compounds.

Conclusions:

  • The year 2022 was highly productive in the discovery of novel marine natural products.
  • The diversity of MNPs underscores the importance of marine ecosystems as a source for new drug leads.
  • Further research into MNP biosynthesis and synthesis is crucial for unlocking their therapeutic potential.