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Correlation Between Radiologic and Histopathologic Features of Orbital Epidermoid and Dermoid Cysts
Hee Jee Yun1, Jeong Hee Kim2, Kyung In Woo1
1Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Ophthalmic Plastic and Reconstructive Surgery
|January 29, 2024
Summary
Orbital epidermoid cysts (EC) and dermoid cysts (DC) show distinct CT features. Differentiating these orbital cysts preoperatively is possible using computed tomography (CT) based on radiodensity and bony changes.
Area of Science:
- Ophthalmology
- Radiology
- Pathology
Background:
- Orbital epidermoid cysts (EC) and dermoid cysts (DC) are common lesions.
- Distinguishing between EC and DC preoperatively can be challenging.
Purpose of the Study:
- To clarify the radiologic and histopathologic characteristics of orbital EC and DC.
- To determine the correlations between radiologic and histopathologic features.
- To evaluate the potential for preoperative differentiation of orbital EC and DC using CT.
Main Methods:
- Retrospective review of 69 patients with orbital EC or DC.
- Analysis of CT findings including size, location, enhancement, content homogeneity, and bony remodeling.
- Histopathological examination of cyst lining and contents.
Main Results:
- Dermoid cysts (DC) were more common (85.5%) than epidermoid cysts (EC) (14.5%).
- Orbital CT revealed significant differences in average radiodensity between EC (18.9 HU) and DC (-67.9 HU).
- Bony remodeling and notching were more frequent in DC.
Conclusions:
- Radiologic and histopathologic features of orbital EC and DC are correlated.
- Computed tomography (CT) can differentiate between orbital EC and DC preoperatively.
- Key differentiating factors include average radiodensity and patterns of bony remodeling.
