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Related Experiment Video

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Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research
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Improving multimodal physical function in adults with heterogeneous chronic pain; Protocol for a multisite

Julia E Hooker1, Julie R Brewer2, Katherine A McDermott1

  • 1Center for Health Outcomes and Interdisciplinary Research, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, United States; Harvard Medical School, Boston, MA, United States.

Contemporary Clinical Trials
|January 29, 2024
PubMed
Summary

This study is testing a mind-body program for chronic pain patients to improve physical function across diverse groups. Results will guide a larger trial on this feasible and acceptable intervention.

Keywords:
Chronic painFeasibilityMind-bodyPhysical functionStep count

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Area of Science:

  • Pain Management
  • Rehabilitation Medicine
  • Clinical Trials

Background:

  • Chronic pain significantly impairs physical function, a major patient concern.
  • The GetActive-Fitbit program shows promise for improving physical function in sedentary individuals with pain.
  • Multisite feasibility is crucial for diverse populations before a large-scale efficacy trial.

Purpose of the Study:

  • To test multisite fidelity of clinician training for the GetActive-Fitbit program.
  • To evaluate recruitment benchmarks for diverse chronic pain patients, including minorities and those with low step counts.
  • To optimize the study protocol for a future multisite efficacy trial.

Main Methods:

  • A multisite randomized controlled trial (RCT) comparing GetActive-Fitbit with a Healthy Living for Pain control group.
  • Assessment of clinician training fidelity through roleplays and mock sessions.
  • Evaluation of feasibility (recruitment, acceptability, adherence) and multimodal physical function at multiple time points.

Main Results:

  • The trial is ongoing with clinician training complete.
  • 87 participants recruited; 54 completed baseline, 44 are mid-intervention, and 9 completed the intervention.
  • Data collection is in progress to assess feasibility and outcomes.

Conclusions:

  • This study is vital for developing feasible and acceptable mind-body interventions for diverse chronic pain populations.
  • Findings will inform the design of a future large-scale multisite efficacy trial.
  • Optimizing the protocol ensures readiness for robust clinical trials.