Related Experiment Video
Updated: Jul 4, 2025

Extinction Training During the Reconsolidation Window Prevents Recovery of Fear
Published on: August 24, 2012
Retrograde amnesia for the stress-induced impairment of extinction: time-dependent and not so forgotten
James F Briggs1, Kaitlyn M McMullen2
1Department of Psychology, Susquehanna University, Selinsgrove, Pennsylvania 17870, USA briggsj@susqu.edu.
Abstract:
We investigated whether retrograde amnesia for the stress-induced impairment of extinction retrieval shares similar characteristics with original acquisition memories. The first experiment demonstrated that cycloheximide administered shortly after a single restraint stress session alleviated the impairment of extinction retrieval but not when administered following a longer delay (i.e., the amnesia for stress is time-dependent). A second experiment showed that the retrograde amnesia for stress could be alleviated by a second brief exposure to the stressor. These results demonstrating that amnesia for stress shares characteristics similar to original memories are explained using a retrieval-based memory integration model of retrograde amnesia.
More Related Videos
07:59Using Practice Testing, Public Speaking, and Source Monitoring to Examine the Influences of Learning Strategies and Stress on Episodic Memory
Published on: June 14, 2019
05:49Stress-Enhanced Fear Learning, a Robust Rodent Model of Post-Traumatic Stress Disorder
Published on: October 13, 2018
Related Concept Videos
Traumatic Memory
Amnesia
The severity and duration of memory loss vary depending on the type and underlying cause. Amnesia is classified into two main types: retrograde and anterograde.
Retrograde amnesia is marked by the loss of memories formed before the onset of the condition. Patients may recall distant past events but often forget those occurring shortly before the incident.
Anterograde...
Interference and Decay
Interference occurs when competing memories hinder the retrieval of particular information. It can be classified into two types: proactive and retroactive interference. Proactive...
Repressed Memory
Dissociative Amnesia
Higher Mental Functions of Brain: Learning and Memory