Related Experiment Video
Updated: Jul 22, 2026
10:05
Measurement & Analysis of the Temporal Discrimination Threshold Applied to Cervical Dystonia
Published on: January 27, 2018
9.8K
The "5Ts" screening tool: Enhancements and threshold values for effective TMD identification
C G Liu1,2,3,4,5, A U Yap1,6,7, K Y Fu1,2,3,4,5
1Center for TMD & Orofacial Pain, Peking University School & Hospital of Stomatology, Beijing, China.
Oral Diseases
|January 30, 2024
Summary
This study improved temporomandibular disorder (TMD) screening by adding frequency and pain type details. The enhanced screeners (5Ts-F and 6Ts-F) showed higher accuracy and specificity for identifying TMDs.
Area of Science:
- Oral and Maxillofacial Medicine
- Diagnostic Accuracy Studies
- Screening Tool Development
Background:
- Temporomandibular Disorders (TMDs) represent a significant public health concern.
- Existing screening tools for TMDs, such as the five TMD symptoms (5Ts) screener, may benefit from enhancements for improved diagnostic precision.
- Differentiating between temporomandibular joint (TMJ) and muscle pain, and incorporating symptom frequency, are potential areas for refinement.
Purpose of the Study:
- To enhance the 5Ts screener for TMD diagnosis by integrating symptom frequency and distinguishing TMJ from muscle pain.
- To evaluate the diagnostic accuracy and establish optimal cut-off points for the enhanced TMD screening tools.
- To compare the performance of the enhanced screeners against the original 5Ts.
Main Methods:
- Adult participants (≥18 years) were recruited from a university hospital setting.
- Participants completed demographic surveys and enhanced screening tools: 5Ts with frequency (5Ts-F) and 6 symptoms with frequency (6Ts-F).
- Diagnostic accuracy was assessed using Area Under the Receiver Operating Characteristic Curves (AUCs) following protocolized interviews and clinical examinations based on DC/TMD criteria.
Main Results:
- 324 participants were enrolled, with 86.4% diagnosed with TMDs.
- The original 5Ts demonstrated high accuracy (AUC=0.92).
- The enhanced 5Ts-F and 6Ts-F showed superior diagnostic accuracy (AUCs=0.95/0.96) and significantly improved specificity (97.7%) compared to 5Ts.
Conclusions:
- The enhanced 5Ts-F and 6Ts-F screeners offer improved diagnostic accuracy and notably higher specificity for TMD detection.
- Recommended cut-off scores for screening TMD presence are >1.5 for 5Ts and >2.5 for 5Ts-F/6Ts-F.
- These refined screening tools can aid in the more effective identification of individuals with TMDs.
More Related Videos
Related Concept Videos
01:18Effects of EDTA on End-Point Detection Methods
Different methods, such as visual observance of metal-ion indicators, spectroscopic techniques, and potentiometric methods, can determine the endpoint of an EDTA titration.
In the visual method, metal-ion indicators (metallochromic dyes), which have distinct colors in their free and complex forms, are added to the mixture to signal the titration's end point. They form stable complexes with metal ions, but these complexes are weaker than the corresponding metal–EDTA complexes. As a result, EDTA...
In the visual method, metal-ion indicators (metallochromic dyes), which have distinct colors in their free and complex forms, are added to the mixture to signal the titration's end point. They form stable complexes with metal ions, but these complexes are weaker than the corresponding metal–EDTA complexes. As a result, EDTA...
01:21Tandem Mass Spectrometry
Tandem mass spectrometry is a technique that uses multiple mass analyzers in series to obtain a higher selectivity and reduce chemical noise during analyte detection. Instruments with multiple analyzers separated by an interaction cell enable secondary fragmentation and selected study of the fragment ions.Secondary fragmentations occur in the interaction cell and can be induced by various factors. Fragmentation induced by collision with inert gases, such as N2, Ar, He, etc., is called...