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PD peritonitis in patients undergoing capsule endoscopy: A descriptive study

Mina Khair1,2, Dharmenaan Palamuthusingam1,2,3, Carmel M Hawley2,4,5

  • 1Metro North Kidney Health Service, Royal Brisbane and Women's Hospital, Herston, Queensland, Australia.

Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis
|January 30, 2024
PubMed

Insights

Capsule endoscopy (CE) appears safe for peritoneal dialysis (PD) patients, with no peritonitis observed when performed alone. This suggests PD patients may not need antibiotic prophylaxis before CE.

Area of Science:

  • Nephrology
  • Gastroenterology
  • Medical Device Technology

Background:

  • Peritoneal dialysis (PD) patients face increased peritonitis risk after procedures like colonoscopy.
  • Current guidelines recommend antibiotic prophylaxis before colonoscopy for PD patients.
  • The peritonitis risk associated with capsule endoscopy (CE) in PD patients is currently unknown.

Purpose of the Study:

  • To assess the risk of peritoneal dialysis-associated peritonitis (PD peritonitis) in PD patients undergoing capsule endoscopy (CE).

Main Methods:

  • A binational data-linkage study analyzed PD patients who underwent CE between 2006 and 2015 in Australia and New Zealand.
  • Descriptive statistics were used to evaluate patient characteristics and clinical outcomes.
  • The study specifically examined peritonitis incidence within 7 days of CE procedures.

Main Results:

  • Overall, 23 PD patients underwent CE.
  • Twelve patients who underwent CE alone experienced no PD peritonitis.
  • Two of 11 patients who underwent CE with other invasive procedures developed PD peritonitis.

Conclusions:

  • Capsule endoscopy (CE) is likely a relatively safe procedure for peritoneal dialysis (PD) patients.
  • PD patients undergoing CE alone may not require pre-procedure antibiotic prophylaxis.
  • CE may serve as a valuable diagnostic tool for gastrointestinal issues in select PD patients.

Keywords:
Capsule endoscopyPD peritonitisperitoneal dialysis-associated peritonitis

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