Use of a leadless pacemaker in the management of swallow syncope: A case report

Daniel G Brieger1, Geoffrey Tofler1,2, Karin K M Chia1,2

  • 1Department of Cardiology, Royal North Shore Hospital, St Leonards, Sydney, New South Wales, Australia.

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Positive inotropic agents are commonly used as the first line of treatment for heart failure. One such agent is digoxin, derived from the genus Digitalis, which has been known for centuries but effectively utilized since 1785. However, these cardiac glycosides can have potentially toxic effects due to their mechanism of action, which involves inhibiting Na+/K+-ATPase and increasing contractility. Digoxin is absorbed orally and distributed in various tissues, including the CNS. It has a long...
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