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Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

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The relationship between sensory processing sensitivity and medication sensitivity: brief report.

Jadzia Jagiellowicz¹, Bianca P Acevedo², Teresa Tillmann³

¹Department of Psychology, Stony Brook University, Stony Brook, NY, United States.

Frontiers in Psychology

|January 31, 2024

Summary

This summary is machine-generated.

Individuals with sensory processing sensitivity (SPS) show increased sensitivity to medications. This trait, also known as being a highly sensitive person (HSP), impacts how people react to various stimuli and treatments.

Keywords:

adverse drug reactions (ADR)environmental sensitivity gender medication adherence medication sensitivity personalized and precision medicine (PPM)pharmacogenomics sensory processing sensitivity (SPS)

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Area of Science:

Psychology
Pharmacology
Neuroscience

Background:

Sensory processing sensitivity (SPS) is a heritable trait characterized by heightened awareness and reactivity to environmental stimuli.
Individuals with SPS may exhibit amplified responses to a wide range of stimuli, potentially including pharmacological agents.

Purpose of the Study:

To investigate the relationship between sensory processing sensitivity (SPS) and medication sensitivity.
To determine if SPS is a significant predictor of medication sensitivity, independent of negative affectivity and gender.

Main Methods:

Three studies were conducted with adult participants (N = 125, 214, 351) from university and online samples.
Participants completed self-report measures including a medication sensitivity scale, the highly sensitive person (HSP) scale for SPS, and a negative affectivity (NA) scale.
Statistical analyses examined correlations between SPS and medication sensitivity, controlling for NA and gender.

Main Results:

All three studies revealed moderate, significant positive correlations between SPS and medication sensitivity (r = 0.34, 0.21, 0.36).
These associations remained significant after controlling for negative affectivity and gender.
No significant interactions were found between SPS and gender regarding medication sensitivity.

Conclusions:

Sensory processing sensitivity (SPS) is significantly associated with medication sensitivity.
SPS should be considered in future research and clinical practice concerning medication recommendations, dosage, efficacy, and adverse drug reactions.
The findings highlight the importance of considering individual differences in sensory processing when evaluating medication responses.