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Secondary breast lymphoma: A case report.
Yazmin Olivares Antúnez1, Yesika Janett Dávila Zablah1, José Raúl Vázquez Ávila2
1Diagnostic Breast Imaging Center of Zambrano-Hellion Hospital, Tecnológico de Monterrey, Av. Batallón de San Patricio 112, Real San Agustín, 66260 San Pedro Garza García, Nuevo León, Mexico.
Radiology Case Reports
|January 31, 2024
Summary
This case highlights Non-Hodgkin's Lymphoma recurrence in the breast, a rare condition often mistaken for other breast pathologies. Early detection through imaging is crucial for managing this hematologic malignancy.
Area of Science:
- Oncology
- Radiology
- Hematology
Background:
- Breast lymphoma is a rare hematologic malignancy, accounting for less than 1% of all breast cancers.
- Secondary B-cell lymphoma is the most common subtype, often presenting as a diagnostic challenge.
- Lymphomas are clinically categorized into primary and secondary breast lymphoma.
Observation:
- A 49-year-old female, recently treated for Non-Hodgkin's Lymphoma, presented with a palpable right breast lump.
- Mammography revealed a dense, circumscribed mass; ultrasound showed a 3.6 cm hypoechoic mass with internal vascularity.
- Axillary nodes exhibited cortical thickening and abnormal vascularity, indicative of nodal involvement.
Findings:
- Histopathology confirmed infiltration of the right breast and bilateral axillary nodes by Non-Hodgkin's Lymphoma.
- The findings represent a recurrence of lymphoma in the breast.
- Imaging findings mimicked both benign and malignant breast conditions, underscoring diagnostic complexity.
Implications:
- Accurate diagnosis of breast lymphoma requires a high index of suspicion and correlation of imaging findings with histopathology.
- This case emphasizes the importance of vigilant follow-up for lymphoma patients presenting with new breast masses.
- Recognizing imaging features of breast lymphoma recurrence is critical for timely and appropriate patient management.
