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Updated: Jul 4, 2025
Tissue Characterization after a New Disaggregation Method for Skin Micro-Grafts Generation
Published on: March 4, 2016
Safety and Efficacy of Mucograft Porcine Collagen Bioengineered Acellular Dermal Matrix as a Spacer Graft in Lower
Richard Parker1,2, Megha Kaushik1,2, Oshin Bansal1
1From NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital, London, UK.
Background:
Recent regulatory changes have limited the access to a widely used commercially available bioengineered acellular dermal matrix (BADM) product as a spacer graft in the surgical correction of lower eyelid retraction. We report our off-label usage of Mucograft, a porcine BADM, as an alternative BADM.
Methods:
A retrospective review was conducted of patients undergoing bilateral lower lid surgery with Mucograft (12 eyes) at a single institution.
Results:
For the six patients, there was a mean lower lid elevation of 1.93 mm, without any serious complications. There was greater elevation of the lower lid position for the Mucograft group compared with four septo-retractor control patients (1.93 versus 0.94mm, P = 0.008).
Conclusion:
Mucograft performed satisfactorily, and further investigation is warranted regarding its longer-term safety and efficacy.
