Anaesthetic implications of hereditary angioneurotic oedema

Hereditary angioneurotic oedema (HANE) presents the danger of laryngeal oedema that may, among other causes, be triggered by the anaesthetist's manipulation of the patient's airway. Local and regional anaesthesia are usually recommended. This report pertains to a patient who successfully tolerated general endotracheal anaesthesia and whose management included prophylactic treatment with danazol and fresh-frozen plasma.