Success and Complication Rates of Revascularization Procedures for Immature Necrotic Teeth: A Systematic Review.

Area of Science:

• Dentistry
• Endodontics
• Regenerative Medicine

Background:

• Adolescent immature necrotic teeth present challenges due to thin root walls and open apices.
• Standard endodontic procedures are often impractical for sealing immature root canals.
• Revascularization therapy and apexification are key treatment strategies.

Purpose of the Study:

• To systematically compare the efficacy of revascularization therapy versus apexification for treating immature necrotic teeth.
• To evaluate clinical and radiographic outcomes, including success rates and complications.

Main Methods:

• A systematic review of randomized clinical trials published between 2001 and 2023.
• Inclusion of 15 studies after screening 850 articles.
• Assessment of periapical healing, overall effectiveness, and apical closure.

Main Results:

• No significant differences were found in periapical healing, overall effectiveness, or apical closure rates between the two groups.
• Revascularization therapy demonstrated a significant increase in root length compared to apexification.
• Revascularization therapy showed enhanced root thickening and a lower rate of overall treatment failure.

Conclusions:

• Both revascularization endodontic therapy and apexification effectively treat periapical periodontitis and promote open apex closure.
• Pulp revascularization offers advantages in root development (length and thickening) and reduces the likelihood of treatment failure.