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Updated: Jul 4, 2025

Intratracheal Inoculation of Fischer 344 Rats with Francisella tularensis
Published on: September 30, 2017
Confirmed Case of Longstanding Respiratory Francisella tularensis holarctica Infection: Nebraska, 2022
Rachael Birn1,2,3, Jeff Hamik1,4, Lana Dayne5
1Epidemiology Unit, Nebraska Department of Health and Human Services, Lincoln, Nebraska, USA.
Abstract:
A male patient with distant history of extensive rabbit contact and pulmonary nodules for 6 years developed empyema. Francisella tularensis holarctica was isolated from thoracentesis fluid. Retrospective immunohistochemical examination of a pulmonary nodule, biopsied 3 years prior, was immunoreactive for F. tularensis. These findings suggest the potential for chronic tularemia.
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