The Craniofacial Collaboration UK: Developmental Outcomes in 7- and 10-Year-Old Children With Metopic Synostosis

Laura Edwards-Bailey1, Katie Piggott1, Louise Dalton2

  • 1Craniofacial Unit, Alder Hey Children's NHS Foundation Trust, Liverpool.

PubMed

Insights

The Craniofacial Collaboration (CC-UK) found most children with metopic synostosis (MS) have average cognitive and behavioral skills. However, some subtle difficulties, especially in parent-reported outcomes, warrant further investigation.

Area of Science:

  • Pediatric Psychology
  • Craniofacial Surgery
  • Neurodevelopmental Disorders

Background:

  • The Craniofacial Collaboration (CC-UK) addresses limitations in craniofacial literature by analyzing homogenous samples of children with craniosynostosis.
  • Previous CC-UK studies examined children with metopic synostosis (MS) and sagittal synostosis at 3 and 5 years.
  • This study extends analysis to older age groups (7 and 10 years) with MS.

Purpose of the Study:

  • To present the fifth wave of CC-UK data collection focusing on cognitive assessments in children with MS.
  • To analyze cognitive assessment data using the Wechsler Abbreviated Scale of Intelligence-Second Edition for children with MS.
  • To compare findings with previous CC-UK analyses and consider implications for clinical practice and future research.

Main Methods:

  • Data collection from 7- and 10-year-old children who underwent primary corrective surgery for metopic synostosis (MS).
  • Cognitive assessment using the Wechsler Abbreviated Scale of Intelligence-Second Edition.
  • Analysis of behavioral and neurodevelopmental domains, including parent-reported outcomes.

Main Results:

  • The majority of children with MS fall within average ranges for behavioral and neurodevelopmental domains.
  • A trend of heightened concern was observed in several domains compared to normative data, particularly in parent-reported outcomes.
  • Subtle difficulties may be present for children with MS, indicated by specific outcome measures.

Conclusions:

  • While most children with MS demonstrate average cognitive functioning, subtle challenges may exist.
  • Longitudinal analyses and multi-perspective data (school, parents, self) are needed for older children.
  • Findings inform clinical practice and highlight the need for continued collaborative research in craniofacial anomalies.