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Updated: Jul 4, 2025

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OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery
Published on: May 9, 2021
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An update on the current indications for in vitro maturation.
Vu N-A Ho1, Tuong M Ho1, Lan N Vuong1,2
1IVFMD and HOPE research center, My Duc Hospital.
Current Opinion in Obstetrics & Gynecology
|January 31, 2024
Summary
In vitro maturation (IVM) is a safe and effective assisted reproductive technique. Expanding indications and improved methods make IVM an accessible option for more patients seeking fertility treatments.
Area of Science:
- Assisted Reproductive Technologies
- In Vitro Maturation (IVM)
- Reproductive Medicine
Background:
- In vitro maturation (IVM) is increasingly integrated into assisted reproductive techniques.
- Published data support the safety and effectiveness of IVM treatments.
- Recent investigations explore expanded indications for IVM.
Purpose of the Study:
- To review advancements in IVM techniques and efficacy evaluation.
- To discuss emerging applications of IVM beyond traditional uses.
- To highlight the potential of IVM for a broader patient population.
Main Methods:
- Review of published data on IVM efficacy and safety.
- Analysis of recent studies on IVM indications and outcomes.
- Assessment of IVM's advantages over conventional in vitro fertilization.
Main Results:
- Significant improvements in IVM techniques and data supporting its efficacy.
- IVM offers advantages over in vitro fertilization for certain patient groups.
- Growing indications for IVM include gonadotropin resistance ovary syndrome and fertility preservation.
Conclusions:
- IVM is a safe, effective, and increasingly accessible fertility treatment.
- Understanding IVM from basic science to clinical practice enhances its application.
- Continued advancements are expected to broaden the impact of IVM in reproductive medicine.

