Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Imaging Biological Samples with Optical Microscopy

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A tumour-host feed-forward loop contributes to the growth of chromosomal instability-induced tumours.

EMBO reports·2026

Same author

Antonio García-Bellido (1936-2025).

Development (Cambridge, England)·2026

Same author

Proteostasis failure and mitochondrial dysfunction contribute to chromosomal instability-induced microcephaly.

Nature communications·2026

Same author

A single WNT enhancer drives specification and regeneration of the Drosophila wing.

Nature communications·2022

Same author

Eiger/TNFα-mediated Dilp8 and ROS production coordinate intra-organ growth in Drosophila.

PLoS genetics·2019

Same author

Epithelial tumors: Growing from within.

Fly·2018

Search research articles

Related Experiment Video

Updated: May 4, 2026

Techniques for Investigating the Anatomy of the Ant Visual System

Techniques for Investigating the Anatomy of the Ant Visual System

Published on: November 27, 2017

Size precision in insect eyes.

Marco Milán^1,2

¹Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.

|January 31, 2024

Summary

Scientists discovered how to precisely control organ size in adult fruit flies. This mechanism uses morphogen signaling to regulate cell survival, ensuring proper organ proportions for functional development.

Area of Science:

Developmental biology
Genetics
Cell biology

Background:

Organ size is crucial for organismal function and development.
Precise regulation of organ size is a complex biological process.
Understanding the mechanisms controlling organ size is essential for developmental biology.

Purpose of the Study:

To investigate the mechanism controlling adult Drosophila eye size.
To identify how morphogen signaling influences cell survival in organ development.

Main Methods:

Utilized Drosophila melanogaster as a model organism.
Employed genetic and live imaging techniques to study cell behavior.
Analyzed morphogen distribution and its effect on cell survival pathways.

More Related Videos

Automated Charting of the Visual Space of Housefly Compound Eyes

Automated Charting of the Visual Space of Housefly Compound Eyes

Published on: March 31, 2022

A Rapid, Simple Workflow for Quantification of External Adult Drosophila Structures

A Rapid, Simple Workflow for Quantification of External Adult Drosophila Structures

Published on: November 8, 2024

Related Experiment Videos

Last Updated: May 4, 2026

Techniques for Investigating the Anatomy of the Ant Visual System

Techniques for Investigating the Anatomy of the Ant Visual System

Published on: November 27, 2017

Automated Charting of the Visual Space of Housefly Compound Eyes

Automated Charting of the Visual Space of Housefly Compound Eyes

Published on: March 31, 2022

A Rapid, Simple Workflow for Quantification of External Adult Drosophila Structures

A Rapid, Simple Workflow for Quantification of External Adult Drosophila Structures

Published on: November 8, 2024

Main Results:

Identified a novel mechanism for size regulation in the adult Drosophila eye.
Demonstrated that morphogen-mediated signaling precisely modulates cell survival.
Showcased the link between morphogen gradients and cell fate decisions.

Conclusions:

Morphogen-mediated modulation of cell survival is key to precise organ size control.
This study provides insights into the developmental mechanisms ensuring proportional organ growth.
Findings contribute to the understanding of how genetic and cellular factors interact to determine organ size.