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Microbiota-derived butyrate restricts tuft cell differentiation via histone deacetylase 3 to modulate intestinal type

Emily M Eshleman1, Taylor Rice1, Crystal Potter2

  • 1Division of Immunobiology, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA; Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Immunity
|January 31, 2024
PubMed

Keywords:
HDAC3butyratedevelopmentepigeneticsintestinemicrobiotaorganoidstem celltuft celltype 2 immunity

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