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Updated: Jul 17, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Ablation of epicardial ventricular focus through coronary sinus using pulsed-field ablation. A case report
Ivica Premuzic Mestrovic1, Toni Breskovic2, Matija Markovic1
1Department of Cardiology, Clinical Hospital Merkur, Zagreb, Croatia.
Introduction:
With the entry of pulsed-field ablation (PFA) into electrophysiology, new possibilities for ablation of different substrates such as epicardial foci of premature ventricular contractions (PVCs) from coronary venous system (CVS) have been opened.
Methods:
This article focuses on a case of a 27-year-old patient with frequent monomorphic PVCs of epicardial origin, treated by radiofrequency ablation, followed by PFA.
Results:
After unsuccessful focus ablation through CVS with RFA, successful ablations from the same region with PFA were achieved.
Conclusion:
This is the first described case of successful ablation of epicardial PVCs using PFA, which we hope will help in defining indications for this novel technology and enhance quality of treatment for patients with different arrhythmias.
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