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05:45
Quantitative Immunohistochemistry of the Cellular Microenvironment in Patient Glioblastoma Resections
Published on: July 31, 2017
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RETROSPECTIVE EVALUATION OF MRI PATTERN OF GLIOBLASTOMA IN A TERTIARY HOSPITAL IN NIGERIA
G I Ogbole1, O A Ogunleye1, M C Nweke2
1Department of Radiology, College of Medicine, University of Ibadan and University College Hospital, Ibadan.
Annals of Ibadan Postgraduate Medicine
|February 1, 2024
Summary
This study describes Glioblastoma imaging characteristics in African patients using conventional MRI. Findings show inhomogeneous enhancement and significant midline shift, with intra-tumoral bleeding being uncommon.
Area of Science:
- Neurology
- Radiology
- Oncology
Background:
- Glioblastomas are aggressive brain cancers with poor prognoses.
- Conventional magnetic resonance (MR) imaging is crucial for characterizing cerebral tumors.
Purpose of the Study:
- To detail the MR imaging features of Glioblastoma in African patients.
- To contribute to the understanding of Glioblastoma presentation in diverse populations.
Main Methods:
- Retrospective cross-sectional study of 14 Glioblastoma patients.
- Analysis of demographic data and conventional MR images.
- Data analyzed using descriptive statistics (SPSS v20.0).
Main Results:
- Glioblastoma identified in 11.5% of brain tumor cases.
- Male-to-female ratio of 2.5:1; mean age 49.6 years.
- All tumors exhibited inhomogeneous enhancement and significant midline shift (>3mm); intra-tumoral bleed was rare (7.1%).
Conclusions:
- Glioblastoma presents with characteristic MR imaging findings.
- Midline shift is a common feature, while intra-tumoral bleeding appears uncommon at initial presentation in this cohort.
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