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Updated: Jul 4, 2025
A Sensitive Visual Method for the Detection of Hydrogen Sulfide Producing Bacteria
Published on: June 27, 2022
A Highly Selective Fluorescent Probe for Hydrogen Sulfide and its Application in Living Cell
Zhiyu Ju1, Yuxiang Zhang2, Lingyu Kong2
1Key Laboratory of Micro-Nano Materials for Energy Storage and Conversion of Henan Province, Drug Intermediates Engineering Research Center for Cleaner Production of Henan Province, College of Chemical and Materials Engineering, Xuchang University, Henan, 461000, PR China. juz1696@163.com.
Abstract:
A new Near-infrared fluorescent probe for hydrogen sulfide detection was synthesized by employing dicyanoisophorone based fluorescence dye as a fluorophore and methyl 3-(2-(carbonyl)phenyl)-2-cyanoacrylate group as the response unit. The Probe DCI-H2S showed a long emission wavelength (λem = 674 nm). Based on the H2S-induced addition-cyclization of deprotecting methyl 3-(2-(carbonyl)phenyl)-2-cyanoacrylate group, the probe DCI-H2S showed high selectivity, sensitivity and response speed toward hydrogen sulfide under room temperature. These numerous advantages of the probe DCI-H2S make it to potentially detect endogenous hydrogen sulfide in living organisms.
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