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Protein Networks

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...

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Related Experiment Video

Updated: Jul 4, 2025

Analysis of Endocytic Uptake and Retrograde Transport to the Trans-Golgi Network Using Functionalized Nanobodies in Cultured Cells

Analysis of Endocytic Uptake and Retrograde Transport to the Trans-Golgi Network Using Functionalized Nanobodies in Cultured Cells

Published on: February 21, 2019

NanoLAS: a comprehensive nanobody database with data integration, consolidation and application.

Shuchang Xiong, Zhengwen Liu¹, Xin Yi¹

¹College of Big Data and Internet, Shenzhen Technology University, Shenzhen 518118, China.

Database : the Journal of Biological Databases and Curation

|February 1, 2024

Summary

Researchers have developed a comprehensive nanobody database to address limitations in existing resources. This new system enhances data accessibility and retrieval, accelerating nanobody research and therapeutic applications.

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Selection of Transporter-Targeted Inhibitory Nanobodies by Solid-Supported-Membrane SSM-Based Electrophysiology

Selection of Transporter-Targeted Inhibitory Nanobodies by Solid-Supported-Membrane SSM-Based Electrophysiology

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Analysis of Endocytic Uptake and Retrograde Transport to the Trans-Golgi Network Using Functionalized Nanobodies in Cultured Cells

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Published on: February 21, 2019

Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions

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Published on: December 1, 2020

Selection of Transporter-Targeted Inhibitory Nanobodies by Solid-Supported-Membrane SSM-Based Electrophysiology

Selection of Transporter-Targeted Inhibitory Nanobodies by Solid-Supported-Membrane SSM-Based Electrophysiology

Published on: May 3, 2021

Area of Science:

Biotechnology
Immunology
Drug Discovery

Background:

Nanobodies, derived from camelids, offer advantages over conventional antibodies due to their small size.
The rapid growth in nanobody research is hindered by inadequate and limited existing antibody databases.

Purpose of the Study:

To create a comprehensive nanobody database integrating data from diverse sources.
To provide researchers with an improved interface for searching and visualizing nanobody data.

Main Methods:

Amalgamation of nanobody data from multiple existing repositories.
Development of a user-friendly search and data display interface for the nanobody database.

Main Results:

A new, comprehensive nanobody database has been successfully assembled.
The database includes the latest nanobody data and offers enhanced search functionalities.

Conclusions:

The Nanobody Library and Archive System significantly improves nanobody data retrieval efficiency.
This resource is expected to accelerate nanobody research, development, and application in biomedicine.