State-of-the-Art Review: Use of Antimicrobials at the End of Life

Daniel Karlin1, Christine Pham2,3, Daisuke Furukawa4

  • 1Division of General Internal Medicine, Department of Medicine, University of California, Los Angeles, California, USA.

Insights

Infectious disease (ID) physicians face challenges guiding antibiotic use at the end of life. Effective communication supports shared decision-making and antibiotic stewardship, aligning care with patient goals.

Area of Science:

  • Medical Ethics
  • Infectious Diseases
  • Palliative Care

Background:

  • Antibiotic use at the end of life presents unique challenges for infectious disease (ID) physicians.
  • ID physicians are well-positioned to guide treatment due to continuity of care for complex infections.
  • Patient-centered care and shared decision-making are paramount in end-of-life antibiotic management.

Purpose of the Study:

  • To explore the role of ID physicians in end-of-life antibiotic decision-making.
  • To identify communication strategies that support shared decision-making and patient values.
  • To enhance antibiotic stewardship in palliative care settings.

Main Methods:

  • Qualitative analysis of physician experiences and perspectives.
  • Review of communication strategies in palliative care.
  • Framework development for shared decision-making in end-of-life infections.

Main Results:

  • ID physicians require specialized communication skills to navigate end-of-life antibiotic choices.
  • Aligning antibiotic therapy with patient goals and values is crucial.
  • Shared decision-making models can be adapted for antibiotic stewardship.

Conclusions:

  • ID physicians play a vital role in end-of-life antibiotic management.
  • Enhanced communication skills are essential for effective patient-centered care.
  • Integrating stewardship principles into palliative care improves outcomes.

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