Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Pneumonia I: Introduction

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...

Pneumonia IV: Management

Pneumonia IV: Management

The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:

Pneumonia III: Complications and Assessment

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:

Pulmonary Tuberculosis I

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...

Transmission-based Precautions II: Airborne and Protective Environment

Transmission-based Precautions II: Airborne and Protective Environment

Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...

Pneumonia V: Nursing management and Prevention

Pneumonia V: Nursing management and Prevention

Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Bronchial and Systemic Relationships of <i>Haemophilus</i> in Chronic Obstructive Pulmonary Disease.

International journal of molecular sciences·2026

Same author

Biomarker-guided use of corticosteroids in pneumonia.

Pneumonia (Nathan Qld.)·2026

Same author

Hypercapnic acidosis affects <i>in vitro</i> lung infection response in a pathogen-specific manner.

Frontiers in cellular and infection microbiology·2026

Same author

Epidemiological insights into Haemophilus influenzae and Pseudomonas aeruginosa persistent colonization in non-cystic fibrosis bronchiectasis patients: a longitudinal and multicenter study.

Respiratory research·2026

Same author

Characterisation of the gut-lung axis microbiome in clinically stable patients with chronic obstructive pulmonary disease.

EBioMedicine·2026

Same author

Immunosuppressed patients with COVID-19 pneumonia in ICU: clinical characteristics and factors influencing outcomes.

Pneumonia (Nathan Qld.)·2025

Search research articles

Related Experiment Video

Updated: Jul 4, 2025

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

Risk of Multidrug-Resistant Pathogens in Severe Community-Acquired Pneumonia.

E Campaña-Duel^1,2, M Camprubí-Rimblas^1,2, A Areny-Balagueró^1,2

¹Critical Care Center, Parc Taulí Hospital Universitari, Institut d'Investigació i Innovació Parc Taulí (I3PT-CERCA), Universitat Autònoma de Barcelona, Sabadell, Spain.

Seminars in Respiratory and Critical Care Medicine

|February 1, 2024

Summary

Identifying difficult-to-treat pathogens causing severe community-acquired pneumonia (SCAP) requires better tools. An integrated approach using predictive scores and rapid diagnostics can improve treatment and outcomes.

More Related Videos

A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii

A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii

Published on: January 2, 2017

Growing a Cystic Fibrosis-Relevant Polymicrobial Biofilm to Probe Community Phenotypes

Growing a Cystic Fibrosis-Relevant Polymicrobial Biofilm to Probe Community Phenotypes

Published on: April 19, 2024

Related Experiment Videos

Last Updated: Jul 4, 2025

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii

A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii

Published on: January 2, 2017

Growing a Cystic Fibrosis-Relevant Polymicrobial Biofilm to Probe Community Phenotypes

Growing a Cystic Fibrosis-Relevant Polymicrobial Biofilm to Probe Community Phenotypes

Published on: April 19, 2024

Area of Science:

Infectious Diseases
Pulmonology
Antimicrobial Resistance

Background:

Severe community-acquired pneumonia (SCAP) poses treatment challenges due to difficult-to-treat (DTR) pathogens, leading to limited options and poor outcomes.
Existing predictive scoring systems for DTR pathogens in SCAP exhibit significant heterogeneity in methodology and target pathogens.
Current models demonstrate limited standalone effectiveness in reducing inappropriate antibiotic use or improving patient outcomes.

Approach:

A comprehensive review of predictive scoring systems and rapid diagnostic methods for identifying DTR pathogens in SCAP was conducted.
The review aimed to inform management strategies for early DTR pathogen detection, reduced broad-spectrum antibiotic use, and improved clinical outcomes.
An integrative algorithm combining predictive scores, local epidemiology, and rapid diagnostics is proposed.

Key Points:

Predictive scoring systems for DTR pathogens in SCAP show variability and limited effectiveness individually.
Rapid diagnostic tools, like multiplex PCR, are crucial for swift pathogen and resistance mechanism identification.
In resource-limited settings, rapid tests should be prioritized for high-risk SCAP patients.

Conclusions:

An integrated algorithm incorporating predictive scores and rapid diagnostics is essential for managing SCAP caused by DTR pathogens.
Local epidemiological data and antimicrobial stewardship programs are vital components of effective management strategies.
Optimizing diagnostic and treatment pathways can lead to improved clinical outcomes for SCAP patients.