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Therapeutical Approach to Arterial Hypertension - Current State of the Art

Milica Radosavljevic1, Danijela Vučević2, Janko Samardžić1

  • 1Department of Pharmacology, Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Belgrade, Belgrade, 11000, Serbia.

Current Medicinal Chemistry
|February 2, 2024
PubMed

Insights

Arterial hypertension (AH), a widespread cardiovascular disease affecting 1.28 billion globally, necessitates effective treatment to prevent severe complications. Ongoing research focuses on innovative pharmacotherapy and lifestyle interventions to manage this prevalent chronic condition.

Area of Science:

  • Cardiology and Public Health

Background:

  • Arterial hypertension (AH) is the most prevalent cardiovascular disease globally, impacting 1.28 billion individuals.
  • It is a major contributor to cardiovascular diseases and premature mortality worldwide.
  • Untreated elevated blood pressure can lead to life-threatening complications such as heart failure, stroke, and renal disorders.

Purpose of the Study:

  • To highlight the critical importance of effective hypertension management.
  • To emphasize the need for continuous innovation in antihypertensive pharmacotherapy.
  • To underscore the role of diverse treatment approaches, including lifestyle modifications and novel medications.

Main Methods:

  • Review of current understanding of hypertension prevalence and its complications.
  • Analysis of established and evolving treatment strategies for arterial hypertension.
  • Exploration of the impact of pharmacotherapy advancements on hypertension management.

Main Results:

  • Hypertension affects a significant global population, underscoring the need for effective interventions.
  • A combination of lifestyle changes and pharmacotherapy is crucial for managing blood pressure.
  • The development of new antihypertensive medications is vital for addressing future challenges.

Conclusions:

  • Effective management of arterial hypertension is essential to reduce global morbidity and mortality.
  • A multifaceted approach, integrating lifestyle interventions with pharmacotherapy, is key to achieving normotensive blood pressure.
  • Continued innovation in antihypertensive pharmacotherapy is critical for the future of cardiovascular health.

Keywords:
Arterial hypertensionexacerbating factorshypertensive crisis.nonpharmacologic treatmentpharmacotherapyresistant hypertension

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