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Pacemaker-induced Cardiomyopathy in Patients with Coronary Artery Disease: A Report of Three Cases
Enes Elvin Gul1, Muhammad Salman Ghazni1, Gehad Gamal1
1Division of Cardiac Electrophysiology, Madinah Cardiac Centre, Madinah, Saudi Arabia.
Insights
Pacing-induced cardiomyopathy (PICM) can affect patients with coronary artery disease (CAD) even with preserved ejection fraction. This report discusses three cases, highlighting the need for further research on managing PICM in this population.
Area of Science:
- Cardiology
- Electrophysiology
- Cardiomyopathy Research
Background:
- Pacing-induced cardiomyopathy (PICM) is characterized by reduced left ventricular ejection fraction (LVEF) due to chronic, high-burden right ventricular pacing.
- Cardiac resynchronization therapy (CRT) and conduction system pacing (CSP) are potential management strategies for PICM.
- Acute myocardial infarction is a known predictor of PICM, but guidelines for CRT/CSP in patients with coronary artery disease (CAD) and preserved LVEF are lacking.
Abstract:
Pacing-induced cardiomyopathy (PICM) is defined as a drop in left ventricular ejection fraction (LVEF) in the setting of chronic, high-burden right ventricular pacing. Cardiac resynchronization therapy (CRT) and conduction system pacing (CSP) have been proposed to manage PICM. Although acute myocardial infarction has been described as a predictor of PICM, there are no guideline recommendations for CRT or CSP in patients with coronary artery disease (CAD) and preserved LVEF. In this report, we present and discuss three cases of PICM in patients with CAD and preserved LVEF.
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