Ocular Lichen Planus: A clinicopathologic review

Area of Science:

• Ophthalmology
• Dermatology
• Pathology

Background:

• Lichen planus is a chronic inflammatory condition affecting skin, mucous membranes, and nails.
• Ocular involvement is rare but can cause significant visual impairment.
• Conjunctival scarring is a common and severe manifestation of ocular lichen planus.

Purpose of the Study:

• To review the ocular pathology of lichen planus.
• To highlight the diagnostic challenges and importance of histopathology.
• To emphasize the potential for severe visual compromise.

Main Methods:

• Literature review of ocular lichen planus cases.
• Analysis of clinical and histopathological findings.
• Comparison with other causes of cicatrizing conjunctivitis.

Main Results:

• Ocular lichen planus primarily affects the conjunctiva.
• Conjunctival scarring can mimic other conditions, necessitating biopsy.
• Progression can lead to irreversible vision loss.

Conclusions:

• Ocular lichen planus is a rare entity with potentially severe visual consequences.
• Histopathological examination is essential for accurate diagnosis.
• Timely intervention may be necessary to prevent extensive scarring.