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Updated: Jul 4, 2025

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Breastfeeding decreases the risk of developing psoriasis through to early adulthood
Debojyoti Das1, Joana Thimjo2, Andrea Lebena1
1Division of Pediatrics.
Insights
Exclusive breastfeeding for at least four months may protect against psoriasis development. Early infant formula and high milk consumption were linked to increased psoriasis risk in a large birth cohort study.
Area of Science:
- Dermatology
- Pediatrics
- Nutritional Science
Background:
- Psoriasis is a genetically influenced systemic skin disease.
- Environmental factors trigger psoriasis manifestation.
- Early nutrition is a potential, understudied trigger.
Purpose of the Study:
- To investigate the association between early nutrition and psoriasis risk.
- To identify specific dietary factors influencing psoriasis development in childhood.
Main Methods:
- Analysis of the All Babies in Southeast Sweden (ABIS) prospective birth cohort (n=16,415).
- Data collected via parental questionnaires at birth, 1, and 3 years.
- Psoriasis diagnosis confirmed using national patient and drug registers.
Main Results:
- Breastfeeding < 4 months and infant formula before 4 months increased psoriasis risk (OR 1.84-1.88).
- High milk consumption correlated with higher psoriasis risk (OR 2.53).
- Increased fish consumption, particularly from the Baltic Sea, significantly raised psoriasis risk (OR 9.61).
Conclusions:
- Early nutrition significantly impacts psoriasis manifestation.
- Exclusive breastfeeding for 4 months shows a protective effect against psoriasis.
- Dietary patterns in infancy may play a crucial role in psoriasis etiology.
Background:
Psoriasis is a genetically determined systemic skin disease, although environmental trigger factors are required for disease manifestation. Some of these triggers, such as stress, infections and drug exposure, have been identified.
Objectives:
To explore the role of early nutrition as a risk factor for the development of psoriasis.
Methods:
Parents in the All Babies in Southeast Sweden (ABIS) prospective birth cohort (n = 16 415) answered questionnaires at birth and when their children were aged 1 and 3 years. A diagnosis of psoriasis was determined from the Swedish National Patient Register and National Drug Prescription Register. Statistical analyses were conducted using custom-written R scripts.
Results:
Individuals breastfed for < 4 months and who received infant formula before 4 months of age had a higher risk of psoriasis [odds ratio (OR) 1.84 (P = 0.02) and OR 1.88 (P = 0.02), respectively]. At the 3-year follow-up, the increased consumption of fish, especially from the Baltic Sea, increased the risk of psoriasis (OR 9.61; P = 0.003). In addition, the risk of psoriasis increased following the consumption of a large volume of milk (OR 2.53; P = 0.04).
Conclusions:
Our study underscores, for the first time, the impact of very early nutrition on the manifestation of psoriasis through early adulthood. Exclusive breastfeeding for 4 months appears to be protective.
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