Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Computed Tomography01:10

Computed Tomography

7.6K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
7.6K
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

853
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
853
Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

541
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
541
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

671
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
671
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

973
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
973
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

893
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
893

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

C1 pedicle screw placement risks in patients with ponticulus posticus: a CTA retrospective simulation study.

Journal of orthopaedic surgery and research·2026
Same author

Clinical benefits and current challenges of photon-counting detector CT in vascular imaging.

Radiology advances·2026
Same author

Hallucination at low radiation dose: Evaluation of two deep-learning reconstruction methods in high-resolution chest CT.

Proceedings of SPIE--the International Society for Optical Engineering·2026
Same author

Prognostic value of estimated pulse wave velocity for all-cause and cardiovascular mortality in individuals with cardiovascular-kidney-metabolic (CKM) syndrome: analyses of NHANES 2007-2018.

Diabetology & metabolic syndrome·2026
Same author

The Uncoupling of CT Dose and Noise.

Radiology·2026
Same author

A framework for quantifying and leveraging uncertainty in pre-trained CT denoising model.

IEEE transactions on bio-medical engineering·2026
Same journal

Correction to "On the shape of the radiation survival curve in tumor spheroids: The role of oxygen heterogeneity".

Medical physics·2026
Same journal

Multi-view constrained semi-supervised vertebra detection for 3D ultrasound spine volume.

Medical physics·2026
Same journal

Accuracy of quantitative <sup>177</sup>Lu SPECT/CT imaging: A systematic review.

Medical physics·2026
Same journal

Physics-constrained dual-domain network for CBCT reconstruction from orthogonal X-rays in gynecologic radiotherapy.

Medical physics·2026
Same journal

Decomposition-based harmonization for quantitative PET imaging across scanners and radiotracers.

Medical physics·2026
Same journal

Development and evaluation of an in vivo dose-based monitoring system for electron FLASH radiation therapy.

Medical physics·2026
See all related articles

Related Experiment Video

Updated: May 2, 2026

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement
06:33

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement

Published on: July 29, 2013

11.3K

Channelized hotelling observer-based low-contrast detectability on the ACR CT accreditation phantom: Part II.

Mingdong Fan1, Zhongxing Zhou1, Cynthia McCollough1

  • 1Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.

Medical Physics
|February 2, 2024
PubMed
Summary
This summary is machine-generated.

Channelized Hotelling observer (CHO) provides repeatable low-contrast detectability measurements for CT quality control. This method is practical for routine use, even with advanced imaging techniques.

Keywords:
computed tomography (CT)image qualitymodel observerquality controlradiation dose

More Related Videos

Author Spotlight: A Stable Phantom Material for Optical and Acoustic Imaging
04:54

Author Spotlight: A Stable Phantom Material for Optical and Acoustic Imaging

Published on: June 16, 2023

2.9K
Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities
07:13

Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities

Published on: October 27, 2023

1.1K

Related Experiment Videos

Last Updated: May 2, 2026

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement
06:33

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement

Published on: July 29, 2013

11.3K
Author Spotlight: A Stable Phantom Material for Optical and Acoustic Imaging
04:54

Author Spotlight: A Stable Phantom Material for Optical and Acoustic Imaging

Published on: June 16, 2023

2.9K
Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities
07:13

Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities

Published on: October 27, 2023

1.1K

Area of Science:

  • Medical Imaging Physics
  • Radiology
  • Image Analysis

Background:

  • Routine CT quality control lacks objective, quantitative evaluation for low-contrast detectability correlating with human performance.
  • Channelized Hotelling observer (CHO) is a promising tool but previously considered impractical due to high scan repetition requirements.
  • Previous work optimized CHO for the ACR CT phantom, enabling accurate detectability index (d') measurement with only 1-3 repeat scans.

Purpose of the Study:

  • To validate the repeatability of a CHO-based low-contrast evaluation method.
  • To assess the method's performance across four different CT scanner models.
  • To utilize the American College of Radiology (ACR) CT accreditation phantom for standardization.

Main Methods:

  • Repeatability testing on four CT scanners (Siemens Force/Alpha, Canon Prism/Prime SP).
  • Acquisition of 10 phantom repositionings, with 3 scans per repositioning at 24, 12, and 6 mGy.
  • Application of CHO to assess low-contrast object detectability (4-6 mm) and evaluation of repeatability using P<15%.

Main Results:

  • CHO measurements demonstrated high repeatability (P<15% of 98.8%-99.9%) at 12 mGy with iterative reconstruction (IR) on all tested scanners.
  • Repeatability remained high across different dose levels and object sizes on individual scanners (P<15% ranging from 91.5% to 99.998%).
  • High repeatability was also observed for deep learning reconstructions and photon-counting-detector (PCD)-CT modes (P<15% > 96.5%).

Conclusions:

  • CHO offers highly repeatable measurements for low-contrast detectability on the ACR phantom, exceeding 95% probability within ±15% tolerance.
  • Repeatability is maintained with advanced techniques like deep learning reconstruction and PCD-CT.
  • The study confirms the feasibility of practical CHO implementation for routine CT quality control and performance evaluation.