Diagnosis of small intestinal microperforation by cell morphology detection in abdominal puncture fluid: A case

Yaqin Zheng1, Zijun Li2, Qinbing Zhou3

  • 1Clinical laboratory centre of Longquan People's Hospital Affiliated to Lishui University, Longquan City, Zhejiang Province, China.

Abstract

Insights

Cellular morphology examination of diagnostic abdominal puncture fluid (DAPF) or diagnostic peritoneal lavage (DPL) offers a rapid and effective method for diagnosing small intestinal perforation, particularly after blunt abdominal trauma (BAT). This technique proves valuable when initial imaging is inconclusive.

Area of Science:

  • Trauma surgery
  • Diagnostic cytology
  • Gastrointestinal injury

Background:

  • Early diagnosis of small intestinal microperforation is crucial for patient prognosis.
  • Abdominal computed tomography angiography (CTA) is often considered the gold standard but can miss subtle injuries.
  • Delayed diagnosis of gastrointestinal trauma significantly worsens outcomes.

Observation:

  • A case report details a patient with blunt abdominal trauma (BAT) initially negative for perforation on CTA.
  • The patient developed persistent fever and septic shock post-surgery.
  • Diagnostic abdominal puncture fluid (DAPF) cell morphology examination ultimately identified intestinal perforation.

Findings:

  • Cellular morphology of DAPF/DPL can reveal specific diagnostic components indicative of intestinal perforation.
  • This method provides a rapid and convenient assessment of intra-peritoneal conditions.
  • The examination of abdominal puncture fluid offers unexpected clinical insights.

Implications:

  • Cellular morphology examination of DAPF/DPL is proposed as the simplest, fastest, and most effective diagnostic tool for small intestinal perforation in BAT.
  • The diagnostic utility of DAPF/DPL in traumatic gastrointestinal injury should not be underestimated.
  • This approach offers a vital alternative or adjunct to imaging in diagnosing critical abdominal trauma.

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