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Sleep duration and all-cause mortality among stroke survivors
Wendemi Sawadogo1, Tilahun Adera2, James B Burch2
1Department of Public Health, College of Human and Health Services, Southern Connecticut State University, New Haven, CT, United States; Department of Epidemiology, School of Population Health, Virginia Commonwealth University, Richmond, VA, United States.
Summary
Longer sleep duration (9+ hours) in stroke survivors is linked to a higher risk of death. This finding highlights excessive sleep as a potential indicator of reduced life expectancy post-stroke.
Area of Science:
- Neurology
- Sleep Medicine
- Public Health
Background:
- Sleep duration post-stroke is a potential risk factor for mortality.
- This study investigated the association between sleep duration and mortality in stroke survivors.
Purpose of the Study:
- To test the hypothesis that inadequate sleep duration is associated with increased mortality among stroke survivors.
- To examine the relationship between different sleep durations and all-cause mortality in a stroke survivor cohort.
Main Methods:
- Utilized data from the REasons for Geographic And Racial Differences in Stroke (REGARDS) study, a national longitudinal population-based study.
- Assessed sleep duration (≤6h, 7-8.9h, ≥9h) in stroke survivors between 2013-2016.
- Employed Cox proportional hazards regression to analyze the association between sleep duration and all-cause mortality, adjusting for covariates.
Main Results:
- Included 468 stroke survivors (mean age 76.3 years, 52.6% female).
- Long sleep duration (≥9 hours) was associated with an increased risk of all-cause mortality (HR=1.46, 95% CI=1.01, 2.12) compared to adequate sleep (7-8.9 hours).
- Short sleep duration (≤6 hours) was not significantly associated with increased mortality (HR=1.31, 95% CI=0.90, 1.91).
Conclusions:
- Sleeping 9 or more hours per day is associated with increased all-cause mortality in stroke survivors.
- Excessive sleep duration may serve as a warning sign for poor life expectancy in this population.
- Further research is warranted to understand the mechanisms linking long sleep duration to mortality post-stroke.
