The Clinical Significance of Unplanned Coronary Artery Bypass Grafting in Aortic Root Replacement
Takuya Ogami1, Derek Serna-Gallegos2, Sarah Yousef1
1Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA.
Insights
Unplanned coronary artery bypass grafting (CABG) during aortic root replacement (ARR) occurred in 4.3% of patients and did not increase mortality risk. Smaller body surface area was linked to a higher chance of needing unplanned CABG.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Aortic Surgery
Background:
- Aortic root replacement (ARR) sometimes necessitates unplanned coronary artery bypass grafting (CABG).
- The implications of unplanned CABG during ARR are not well-established.
Purpose of the Study:
- To evaluate the impact of unplanned CABG on mortality in patients undergoing ARR.
- To identify risk factors associated with unplanned CABG during ARR.
Main Methods:
- Retrospective observational study at a single tertiary care center.
- Analysis of 795 patients who underwent ARR between 2011 and 2022.
- Comparison of outcomes between patients with and without unplanned CABG.
Main Results:
- Unplanned CABG was required in 4.3% of ARR patients.
- Indications for unplanned CABG included ventricular dysfunction, disease pathology, anatomy, and surgical complications.
- Unplanned CABG was not associated with increased operative or long-term mortality.
- A body surface area < 1.7 m² was independently associated with a higher risk of unplanned CABG.
Conclusions:
- Unplanned CABG during ARR is infrequent and does not appear to elevate mortality risks.
- Patient body surface area is a significant factor predicting the need for unplanned CABG during ARR.
Objectives:
Unexpected coronary artery bypass grafting (CABG) is occasionally required during aortic root replacement (ARR). However, the impact of unplanned CABG remains unknown.
Design:
A single-center, retrospective observational study.
Setting:
At university-affiliated tertiary hospital.
Participants:
All patients who underwent ARR from 2011 through 2022.
Interventions:
Aortic root replacement with or without unplanned CABG.
Measurements And Main Results:
A total of 795 patients underwent ARR. Among them, 131 (16.5%) underwent planned concomitant CABG, and 34 (4.3%) required unplanned CABG. The most common indication of unplanned CABG was ventricular dysfunction (33.3%), followed by disease pathology (25.6%), anatomy (15.4%), and surgical complications (10.3%). A vein graft to the right coronary artery was the most commonly performed bypass. Infective endocarditis and aortic dissection were observed in 27.8% and 12.8%, respectively. Prior cardiac surgery was seen in 40.3%. The median follow-up period was 4.3 years. Unplanned CABG was not associated with operative mortality (odds ratio [OR] 1.54, 95% CI 0.33-7.16, p = 0.58) or long-term mortality (hazard ratio 0.91, 95% CI 0.44-1.89, p = 0.81). Body surface area smaller than 1.7 was independently associated with an increased risk of unplanned CABG (OR 4.51, 95% CI 1.85-11.0, p < 0.001).
Conclusions:
Unplanned CABG occurred in 4.3% of patients during ARR, but was not associated with operative mortality or long-term mortality. A small body surface area was a factor associated with unplanned CABG.
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