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Longitudinal parental perception of COVID-19 vaccines for children in a multi-site, cohort study

Patrick Rivers1, Cynthia Porter1, Lindsay B LeClair2

  • 1University of Arizona, Tucson, AZ, United States.

Vaccine
|February 2, 2024
PubMed

Insights

Parental beliefs about COVID-19 vaccine safety and effectiveness strongly predict child vaccination. Over time, parental knowledge increased, but vaccine safety and effectiveness beliefs became more negative, highlighting a need for targeted public health policies.

Area of Science:

  • Pediatric infectious disease epidemiology
  • Public health policy
  • Vaccinology

Background:

  • Understanding pediatric COVID-19 vaccine hesitancy and uptake is crucial.
  • Parental knowledge, attitudes, and practices (KAP) influence child vaccination decisions.

Purpose of the Study:

  • To assess COVID-19 vaccine knowledge, attitudes, practices, and uptake in children aged 6 months to 17 years.
  • To examine changes in parental KAP and their impact on vaccine uptake over 15 months.

Main Methods:

  • Prospective cohort study (PROTECT) of 2,837 children.
  • Quarterly collection of sociodemographic data, vaccination status, and parental KAP.
  • Logistic regression and McNemar's test analyzed KAP effects and changes over time.

Main Results:

  • 61% of children were vaccinated by October 2022.
  • Positive parental beliefs on vaccine safety and effectiveness strongly predicted uptake in children aged 5-17 years.
  • Parental knowledge increased, but beliefs regarding vaccine safety, effectiveness, and trust in government became more negative over time.

Conclusions:

  • Parental beliefs regarding COVID-19 vaccine safety and effectiveness are key drivers of pediatric vaccine uptake.
  • Beliefs and knowledge evolve, necessitating public health strategies focused on reinforcing vaccine safety and effectiveness messaging.
Abstract

Keywords:
COVID-19ChildrenVaccine acceptance

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