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Updated: Jul 4, 2025
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Published on: December 25, 2021
Translation regulation in response to stress
Thomas D Williams1,2, Adrien Rousseau1
1MRC-PPU, School of Life Sciences, University of Dundee, UK.
Abstract:
Cell stresses occur in a wide variety of settings: in disease, during industrial processes, and as part of normal day-to-day rhythms. Adaptation to these stresses requires cells to alter their proteome. Cells modify the proteins they synthesize to aid proteome adaptation. Changes in both mRNA transcription and translation contribute to altered protein synthesis. Here, we discuss the changes in translational mechanisms that occur following the onset of stress, and the impact these have on stress adaptation.
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