[Varicella vaccination, pregnancy and breastfeeding: The current situation]
Catherine Vauzelle1, Elisabeth Elefant1, Bénédicte Coulm2
1Département de santé publique, Centre de référence sur les agents tératogènes (CRAT), hôpital Trousseau, Sorbonne université, AP-HP, 75012 Paris, France.
Abstract:
The varicella vaccine is recommended for women with no history of varicella who are planning to become pregnant, as well as for post-pregnancy women, to prevent the occurrence of this illness and its severe complications, especially an embryopathy, when it occurs in a pregnant woman (congenital varicella syndrome). This live attenuated vaccine should not be administered during pregnancy, nor in the month preceding it. However, when this occurs inadvertently, the data collected on the outcomes of exposed pregnancies, although few in women seronegative at the time of vaccination, allow to reassure the patients to date, as no congenital varicella syndrome has been reported to date following accidental vaccination in early pregnancy. On the other hand, during breastfeeding, a woman may be vaccinated if there is an expected short- or medium-term benefit (varicella exposure, planned pregnancy…).
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