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Updated: Jul 4, 2025

Predictive Immune Modeling of Solid Tumors
Published on: February 25, 2020
Clinical decision support systems for multidisciplinary team decision-making in patients with solid cancer:
Mathijs P Hendriks1, Agnes Jager2, Kees C W J Ebben3
1Department of Health Technology and Services Research, Technical Medical Center, University of Twente, PO Box 217, 7500 AE Enschede, the Netherlands; Department of Research and Development, Netherlands Comprehensive Cancer Organisation (IKNL), PO Box 19079, 3501 DB Utrecht, the Netherlands; Department of Medical Oncology, Northwest Clinics, PO Box 501, 1800 AM Alkmaar, the Netherlands.
Abstract:
Generating guideline-based recommendations during multidisciplinary team (MDT) meetings in solid cancers is getting more complex due to increasing amount of information needed to follow the guidelines. Usage of clinical decision support systems (CDSSs) can simplify and optimize decision-making. However, CDSS implementation is lagging behind. Therefore, we aim to compose a CDSS implementation model. By performing a scoping review of the currently reported CDSSs for MDT decision-making we determined 102 barriers and 86 facilitators for CDSS implementation out of 44 papers describing 20 different CDSSs. The most frequently reported barriers and facilitators for CDSS implementation supporting MDT decision-making concerned CDSS maintenance (e.g. incorporating guideline updates), validity of recommendations and interoperability with electronic health records. Based on the identified barriers and facilitators, we composed a CDSS implementation model describing clinical utility, analytic validity and clinical validity to guide CDSS integration more successfully in the clinical workflow to support MDTs in the future.
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