Related Experiment Video
Updated: Jul 4, 2025

Characterization of Complex Systems Using the Design of Experiments Approach: Transient Protein Expression in Tobacco as a Case Study
Published on: January 31, 2014
Representative design: A realistic alternative to (systematic) integrative design
Gijs A Holleman1, Mandeep K Dhami2, Ignace T C Hooge3
1Department of Cognitive Neuropsychology, Tilburg University, Tilburg, the Netherlands g.a.holleman@tilburguniversity.edu.
Abstract:
We disagree with Almaatouq et al. that no realistic alternative exists to the "one-at-a-time" paradigm. Seventy years ago, Egon Brunswik introduced representative design, which offers a clear path to commensurability and generality. Almaatouq et al.'s integrative design cannot guarantee the external validity and generalizability of results which is sorely needed, while representative design tackles the problem head on.
More Related Videos
Related Concept Videos
Design Consideration
The factor of safety is another key...
Experimental Designs
Systematic Sampling Method
Systematic sampling is one of the simplest methods...
Decision Making: Traditional Method
First, a specific claim about the population parameter is decided based on the research question and is stated in a simple form. Further, an opposing statement to this claim is also stated. These statements can act as null and alternative hypotheses, out of which a null hypothesis would be a...
Design Example
The Representativeness Heuristic

