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Management strategies for antidepressant-related sexual dysfunction
Frank Lach1, Hugo Bottemanne2, Coraline Hingray3
1Centre de Ressources et d'Expertise en Psychopharmacologie du Grand'Est (CREPP GE), Établissement Public de Santé Alsace Nord (EPSAN), Brumath, France.
L'Encephale
|February 4, 2024
Summary
Managing antidepressant-induced sexual dysfunction involves strategies like dose reduction, maintenance, or optimizing treatment. Clinicians should tailor choices to patient needs, considering efficacy and tolerance for major depressive disorder patients.
Area of Science:
- Pharmacology
- Psychiatry
- Clinical Medicine
Background:
- Antidepressant-induced sexual dysfunction is a common adverse effect in major depressive disorder treatment.
- Non-pharmacological interventions may not always be sufficient.
- Management strategies are crucial for patient adherence and quality of life.
Purpose of the Study:
- To provide an overview of pharmacological strategies for managing antidepressant-related sexual dysfunction.
- To categorize management approaches for clinicians.
- To guide treatment selection based on patient-specific factors.
Main Methods:
- Review of pharmacological strategies for antidepressant-induced sexual dysfunction.
- Categorization of strategies into tapering, maintenance, and optimizing treatment.
- Consideration of antidepressants and corrective medications available in France.
Main Results:
- Management strategies are divided into three main groups: tapering, maintenance, and optimizing treatment.
- Tapering includes dose reduction or short-term interruption.
- Optimizing treatment involves substitution or adding corrective medications.
Conclusions:
- Clinicians should select the most appropriate strategy based on treatment efficacy, tolerance, sexual dysfunction phase, and patient preferences.
- Personalized therapeutic options are essential for managing antidepressant-induced sexual dysfunction.
- This overview focuses on treatments available in France for clinical guidance.
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