Related Experiment Video
Updated: Jul 4, 2025
Laparoscopic Anterior Right Hepatectomy: A Single-Center Experience
Published on: December 4, 2023
Laparoscopic anatomic vs. nonanatomic liver resection for large hepatocellular carcinoma (≥5 cm) in the right lobe
Ahmed R Badawy1, Ho-Seong Han2, Tamer M El-Mahdy3
1Department of Surgery, Seoul National University Bundang Hospital, Seoul National University, College of Medicine, Seoul, South Korea; Department of General Surgery, Faculty of Medicine, Tanta University, Tanta, Egypt.
Objective:
To determine the impacts and outcomes of laparoscopic anatomic liver resection (LAR) and laparoscopic nonanatomic resection (LNAR) in patients with large hepatocellular carcinoma (HCC) in the right lobe of the liver.
Background:
There are few comparative studies of LAR and LNAR for large HCC.
Method:
Three hundred thirty-seven patients underwent liver resection for large HCC (≥5 cm) at Seoul National University Bundang Hospital, Seoul, Korea, between January 2004 and December 2022. After the exclusion of patients treated with open hepatic resection and those who had left-lobe or bilobar tumors, 94 patients were ultimately included. Patients were divided into LAR group (61 patients) and LNAR group (33 patients). After propensity score matching (PSM) with 1:1 matching, 31 patients were included in each group. The outcomes in the two groups were compared.
Results:
LAR group had longer operative time than LNAR group (333.7 ± 113.7 vs 210 ± 117.6 min, respectively, P < 0.001), wider safety margin (1.4 ± 1.5 vs 0.7 ± 0.7 cm, respectively, P = 0.015), and lower incidence of recurrence (25.8% vs. 54.8%, respectively, P = 0.021).
Conclusion:
LAR required longer operative time, achieved wider safety margin, and had lower incidence of recurrence than LNAR.
