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Published on: April 17, 2020
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Esophageal intramural pseudodiverticulosis.
1Department of Gastroenterology, Japan Community Healthcare Organization Hoshigaoka Medical Center, Hirakata 573-8511, Osaka, Japan. shintakumahoshi@gmail.com.
World Journal of Gastroenterology
|February 5, 2024
Summary
Esophageal intramural pseudodiverticulosis (EIPD) involves cystic dilation of esophageal gland ducts. This review covers EIPD
Area of Science:
- Gastroenterology
- Esophageal Diseases
- Glandular Pathology
Background:
- Esophageal intramural pseudodiverticulosis (EIPD) is a rare condition of unknown cause.
- It features cystic dilation of esophageal submucosal gland ducts.
- EIPD often presents with dysphagia and is associated with infections like candidiasis.
Purpose of the Study:
- To review the epidemiology, clinical, endoscopic, and histopathological features of EIPD.
- To discuss the potential etiology and pathogenesis of EIPD.
- To outline current management strategies for EIPD.
Main Methods:
- Review of literature and author's clinical experience with EIPD.
- Analysis of epidemiological data, clinical presentations, and diagnostic findings.
- Examination of esophagographic and histopathological characteristics.
Main Results:
- EIPD typically affects middle-aged individuals, presenting with dysphagia.
- Esophagography shows flask-shaped projections; endoscopy reveals mucosal depressions.
- Histopathology demonstrates hyperplastic epithelial cells with preserved myoepithelial cells.
Conclusions:
- EIPD management focuses on symptomatic relief and infection prevention.
- The exact cause remains unknown, but autonomic nerve dysfunction is suspected.
- Further research into EIPD pathogenesis is warranted.
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