Related Experiment Video
Updated: Jul 4, 2025
02:15
Predictive Measurement for Windlass Change in Length and Selected Treatment Outcomes in Chronic Plantar Fasciitis
Published on: March 1, 2024
489
A chronic non-healing ulcer plantar
Luisa Unterluggauer1, Ichiro Okamoto1
1Department of Dermatology Medical University of Vienna Vienna Austria.
Skin Health and Disease
|February 5, 2024
Summary
This case study highlights successful immunotherapy for advanced acral melanoma. Treatment with Ipilimumab and Nivolumab achieved a complete response without surgical intervention for the primary tumor or metastases.
Area of Science:
- Oncology
- Dermatology
- Immunotherapy
Background:
- Acral melanoma presents diagnostic challenges and has a poor prognosis once metastatic.
- Therapeutic efficacy for metastatic acral melanoma is often limited compared to other melanoma types.
Purpose of the Study:
- To report a case of advanced acral melanoma.
- To describe the successful use of immunotherapy as a primary treatment modality.
Main Methods:
- Diagnosis of acral melanoma was established after distant metastases were present.
- Treatment initiated with a combination immunotherapy regimen: Ipilimumab and Nivolumab.
Main Results:
- A complete response was achieved in the patient.
- The response was obtained without the need for surgical removal of any tumors, including the primary acral melanoma.
Conclusions:
- Immunotherapy with Ipilimumab and Nivolumab can be an effective primary treatment for metastatic acral melanoma.
- Complete response is achievable without surgery in select cases of advanced acral melanoma.
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