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Updated: Jul 4, 2025

Multicellular Human Alveolar Model Composed of Epithelial Cells and Primary Immune Cells for Hazard Assessment
Published on: May 6, 2020
Hepatitis B vaccination coverage and serological status among health care workers exposed to occupational biological
Fernanda Sucasas Frison1, Herling Gregorio Aguilar Alonzo1, Inajara de Cassia Guerreiro2
1Departamento de Saúde Coletiva, Universidade Estadual de Campinas (Unicamp), Campinas, SP, Brazil.
Introduction:
Health care workers are often exposed to hepatitis B infection during the course of their professional roles.
Objectives:
To analyze the hepatitis B vaccination coverage and the presence of antibodies against hepatitis B among health care professionals who were exposed to contaminated biological material at a hospital complex.
Methods:
This descriptive, retrospective, and quantitative study is based on the analysis of accident notification form data (n = 2,466) from a hospital complex covering the period between 2011 and 2020.
Results:
Among the affected individuals, women (69.5%), medical residents (35.7%), and nursing staff (25.5%) accounted for the highest proportion of hazards. Regarding vaccination status, 98% of the health care professionals reported being fully immunized, and antibodies were detected in 90.9% of the participants. Percutaneous exposure (76.4%) was the most prevalent type of hazard, with blood being the most commonly involved material (79.4%).
Conclusions:
The findings show that despite the risks of Hepatitis B contamination associated with the incidents, the professionals were protected due to the high vaccination coverage and evidence of immunity.
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