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Immuno-fluorescence Assay of Leptospiral Surface-exposed Proteins
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Severe Jarisch-Herxheimer Reaction (JHR) in a leptospirosis patient: A case report

Ruo-Yan Zhao1,2, Meng-Die Liu3,2, Ying-Xin Lin2

  • 1Hubei University of Medicine, Shiyan, 442000, Hubei Province, China.

Heliyon
|February 5, 2024
PubMed

Insights

Leptospirosis, a bacterial zoonosis, can cause severe organ failure. Antibiotic treatment may trigger Jarisch-Herxheimer reaction (JHR), potentially worsening the disease course, as seen in a pulmonary hemorrhagic case.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Clinical Medicine

Background:

  • Leptospirosis is a zoonotic disease with potential for severe organ damage.
  • Current treatment involves antibiotics, which can induce Jarisch-Herxheimer reaction (JHR).
  • The interaction between leptospirosis and JHR is poorly understood.
Keywords:
Acute renal failureAcute respiratory distress syndromeCase reportJarisch-Herxheimer reactionLeptospirosis

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