A novel approach to encode melodies in DNA

DNA data storage has gained more attention last decades. DNA molecules can be used for encoding of non-biological information and as promising carriers due to greater data capacity, higher duration of the storage, and better technical failures stability. Here we propose a new method for encoding of notes and music in DNA. The encoding technique takes into account the duration and tonality of each note, enabling to encode all seven octaves by assigning a nucleotide sequence to each key. A certain set of short sequences is suggested to define the duration of note sound. The proposed method allows to encode more complicated melodies compared to the approach based on Huffman algorithm.