The Image Biomarker Standardization Initiative: Standardized Convolutional Filters for Reproducible Radiomics and...

Philip Whybra¹, Alex Zwanenburg¹, Vincent Andrearczyk¹+43

• ¹From the School of Engineering, Cardiff University, Cardiff, United Kingdom (P.W., E.S.); OncoRay-National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany (A.Z., S.L.); National Center for Tumor Diseases (NCT), Partner Site Dresden, Germany: German Cancer Research Center (DKFZ), Heidelberg, Germany, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany, and Helmholtz Association/Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Fetscherstrasse 74, PF 41 Dresden 01307, Germany (A.Z.); Institute of Informatics, University of Applied Sciences and Arts Western Switzerland (HES-SO), Sierre, Switzerland (V.A., R.S., H.M., A.D.); Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY (A.P.A., A.I.); Department of Computer Science, Université de Sherbrooke, Sherbrooke, QC, Canada (A.A., M.A.L.L., M.V.); Center for Artificial Intelligence and Data Science for Integrated Diagnostics (AI2D) and Center for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, Pa (B.B., S.B., S.P.); Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (B.B., S.B., S.P.); Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (B.B., S.B., S.P.); Division of Computational Pathology, Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Ind (B.B., S.B., S.P.); Department of Medical Physics, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy (A.B., F.M.); Department of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, the Netherlands (R.B.); Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy (L.B., N.D., J.L.); Institut Curie, Université PSL, Inserm U1288, Laboratoire d'Imagerie Translationnelle en Oncologie, Orsay, France (I.B., C.N., F.O.); Department of Cancer Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (G.J.R.C., V.G., C.G.R.); Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Zurich, Switzerland (F.D., H.S.G., M.G., S.T.); Department of Radiology, Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom (V.G.); LaTIM, INSERM, UMR 1101, Université de Bretagne-Occidentale, Brest, France (M. Hatt, F.T.); Technological Virtual Collaboration (TECVICO Corp), Vancouver, Canada (M. Hosseinzadeh, M.R.S.); Department of Electrical and Computer Engineering, Tarbiat Modares University, Tehran, Iran (M. Hosseinzadeh); Department of Radiation Oncology, University of California San Francisco, San Francisco, Calif (O.M., T.U.); Departments of Radiology and Physics, University of British Columbia, Vancouver, Canada (A.R.); Department of Medical Physics, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran (S.M.R.); Repository Unit, Cancer Research UK National Cancer Imaging Translational Accelerator, United Kingdom (C.G.R.); Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada (M.R.S., F.Y.); Department of Nuclear Medicine, Universitätsklinikum Augsburg, Augsburg, Germany (A.S.); Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, Geneva, Switzerland (I.S., H.Z.); Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Switzerland (I.S.); Department of Diagnostic Imaging, Oncological Radiotherapy, and Hematology, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy (V.V.); Department of Radiological and Hematological Sciences, Università Cattolica del Sacro Cuore-Milano, Milan, Italy (V.V.); Department of Radiology, The Netherlands Cancer Institute, Amsterdam, the Netherlands (J.J.M.v.G.); Department of Radiology, UMC Utrecht, Utrecht, the Netherlands (J.J.M.v.G.); Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke (CHUS), Sherbrooke, Canada (M.V.); and Department of Nuclear Medicine and Molecular Imaging, Lausanne University Hospital (CHUV), Lausanne, Switzerland (A.D.).