Related Experiment Video
Updated: Jul 4, 2025
12:22
The Use of Reverse Phase Protein Arrays RPPA to Explore Protein Expression Variation within Individual Renal Cell Cancers
Published on: January 22, 2013
33.6K
[Papillary renal neoplasm with reverse polarity].
1Medico-Biological University of Innovation and Continuing Education of the Burnasyan Federal Medical Biophisical Center, Moscow, Russia.
Arkhiv Patologii
|February 6, 2024
Summary
Papillary renal neoplasm with reverse polarity, a rare kidney tumor subtype, presents unique features and a good prognosis. This case highlights diagnostic challenges and criteria for pathologists and clinicians.
Area of Science:
- Nephrology
- Oncology
- Pathology
Background:
- Papillary renal neoplasm with reverse polarity is a rare subtype of papillary renal cell tumors.
- It is characterized by unique morphology and specific molecular features.
- This subtype generally exhibits a good prognosis.
Observation:
- The article presents literature data and a case observation of a papillary kidney tumor with reverse nuclear polarity.
- The patient was a 73-year-old individual.
- Difficulties in preoperative diagnosis were noted.
Findings:
- Histological and immunohistochemical criteria for diagnosis are presented.
- Differential diagnosis with other kidney tumors is discussed.
- The unique morphology and molecular features are highlighted.
Implications:
- This rare case provides valuable insights for both pathologists and clinicians.
- Understanding diagnostic criteria is crucial for accurate patient management.
- Further research into this specific subtype may improve diagnostic accuracy and treatment strategies.
More Related Videos
Related Concept Videos
01:20The Retinoblastoma Gene
4.1K
Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
4.1K
02:23Abnormal Proliferation
4.5K
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
4.5K
01:12Internal Anatomy of the Kidney
1.7K
The kidneys are essential organs in the human body, performing a myriad of tasks that maintain homeostasis and overall health.
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...
1.7K