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Ischemic Heart Disease: Overview01:17

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Factors Associated With Myocardial Infarction in a Rural Population With Peripheral Arterial Diseases.

Adeola O Awujoola1, Moboni T Mokikan2, Olufeyisayo O Odebunmi3

  • 1Department of Pediatrics, Bronxcare Health System, Bronx, NY, USA.

Angiology
|February 6, 2024
PubMed
Summary
This summary is machine-generated.

Peripheral arterial disease (PAD) patients in rural areas face higher risks of myocardial infarction (MI). Hypertension, diabetes, smoking, and male sex significantly increase MI likelihood in this population.

Keywords:
Appalachiamyocardial infarctionperipheral arterial diseaserisk factorsrural

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Area of Science:

  • Cardiovascular Medicine
  • Public Health
  • Epidemiology

Background:

  • Peripheral arterial disease (PAD) research in rural settings is scarce.
  • Patients with PAD exhibit a higher incidence of myocardial infarction (MI).
  • Central Appalachia faces unique healthcare challenges impacting cardiovascular outcomes.

Purpose of the Study:

  • To investigate the association between sociodemographic, clinical risk factors, and MI incidence.
  • To identify key risk factors for MI in a rural PAD patient cohort in Central Appalachia.
  • To inform targeted prevention strategies for cardiovascular events in underserved populations.

Main Methods:

  • Retrospective analysis of electronic medical records from 5,574 PAD patients.
  • Utilized bivariate and logistic regression analyses to assess risk factors.
  • Focused on a large health system serving 230 counties across six US states.

Main Results:

  • 24.85% of the study cohort (mean age 71) were diagnosed with MI.
  • Hypertension (aOR=3.21), diabetes (aOR=1.51), ever-smoking (aOR=1.34), and male sex (aOR=1.45) were significant predictors of MI.
  • Adjusted analyses controlled for potential confounding variables.

Conclusions:

  • Hypertension, diabetes, smoking, and male sex are critical risk factors for MI in rural PAD patients.
  • Targeted screening and management of these factors are crucial for MI prevention.
  • Interventions in rural Central Appalachia could reduce MI burden in PAD patients.