Prophylactic Radiation Therapy for High-Risk Asymptomatic Bone Metastases: A New Standard of Care or Need for More...

Adrian Wai Chan¹, Charles B Simone¹, Yvette van der Linden¹+14

• ¹Adrian Wai Chan, MBBS, Department of Radiation Oncology, Sunnybrook Health Sciences Centre, the University of Toronto, Toronto, Canada; Charles B. Simone II, MD, Department of Radiation Oncology, New York Proton Center, New York, NY; Yvette van der Linden, MD, PhD, Department of Radiotherapy, Leiden University Medical Centre, Leiden, the Netherlands, Centre of Expertise in Palliative Care, Leiden University Medical Centre, Leiden, the Netherlands; Peter Hoskin, MD, Mount Vernon Cancer Centre, Northwood, United Kingdom, Division of Cancer Sciences, University of Manchester, United Kingdom; Jay Detsky, MD, PhD, Department of Radiation Oncology, Sunnybrook Health Sciences Centre, the University of Toronto, Toronto, Canada; J. Isabelle Choi, MD, Department of Radiation Oncology, New York Proton Center, New York, NY, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY; S.F. Lee, MD, , Department of Radiation Oncology, National University Cancer Institute, National University Hospital, Singapore; Henry CY Wong, MBBS, Department of Clinical Oncology, Tuen Mun Hospital, New Territories West Cluster, Hospital Authority, Hong Kong S.A.R., China, Department of Oncology, Princess Margaret Hospital, Kowloon West Cluster, Hospital Authority, Hong Kong S.A.R., China; Henry CY Wong, MBBS, Department of Medicine, UCLA Health, Los Angeles, CA; Srinivas Raman, MD, Department of Radiation Oncology, Princess Margaret Cancer Center, Toronto, Canada; Dirk Rades, MD, Department of Radiation Oncology, University of Lübeck, Germany; Agata Rembielak, MD, PhD, Department of Clinical Oncology, The Christie NHS Foundation Trust, Manchester, United Kingdom, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom; Joanna Kazmierska, MD, PhD, Radiotherapy Department II, Greater Poland Cancer Centre, Poznan, Poland, Electroradiology Department, University of Medical Sciences, Poznan, Poland; Vassilios Vassiliou, MD, PhD, Department of Radiation Oncology, Bank of Cyprus Oncology Centre, Strovolos, Cyprus; Sara Alcorn, MD, PhD, Department of Radiation Oncology, University of Minnesota Medical School, Minneapolis, MN; Pierluigi Bonomo, MD, Department of Radiation Oncology, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy; and Eva Oldenburger, MD, Department of Radiation Oncology, University Hospital Leuven, Leuven, Belgium.